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This is a list of all the key items that are found in Generation III. Please note that some of these are also part of the list of Key Items in Generation I due to Pokémon Red and Blue being remade, and several appear in multiple generations.

Some items are specific to a certain region, while others can be found in both Kanto and Hoenn.

Item Gen Effect
Acro Bike Acro Bike III Use to move faster than walking. Slower than the Mach Bike, but can perform tricks
AuroraTicket AuroraTicket III Allows players to access Birth Island*
Basement Key III Basement Key III Allows access to New Mauville
Berry Pouch Berry Pouch III Holds Berries
Bicycle Bicycle III Use to move faster than walking
Bike Voucher Bike Voucher III Exchange for Bicycle
Blue Orb III Blue Orb III Use to calm Kyogre
Card Key III Card Key III Opens doors in Silph Co.
Coin Case Coin Case III Holds up to 9999 coins for use at the Rocket Game Corner or Mauville Game Corner
Contest Pass Contest Pass III Allows players to participate in Pokémon Contests
Devon Goods Devon Goods III To be delivered to Captain Stern in Slateport City
Devon Scope III Devon Scope III Reveals hidden Pokémon; Allows access to the Fortree Gym
Eon Ticket Eon Ticket III Allows players to access Southern Island*
Fame Checker Fame Checker III Tells about famous characters
Go-Goggles Go-Goggles III Allows players to enter the desert sandstorm on Route 111
Good Rod Good Rod III Allows the player to fish in bodies of water. Better than the Old Rod
Gold Teeth Gold Teeth III Safari Zone Warden's false teeth. Return them to him for HM04 (Strength)
Itemfinder Itemfinder III Locates items hidden on the ground
Letter Letter III To be delivered to Steven Stone
Lift Key Lift Key III Allows operation of the elevator in the Rocket Hideout
Mach Bike Mach Bike III Use to move much faster than walking. Able to climb muddy slopes
Magma Emblem Magma Emblem III Used to access the Team Magma Hideout
Meteorite Meteorite III Return to Professor Cozmo in exchange for TM27 (Return)RSE
Deliver to Lostelle's father on Two Island at Bill's requestFRLG
MysticTicket MysticTicket III Allows players to access Navel Rock*
Oak's Parcel Oak's Parcel III Deliver to Professor Oak to receive a Pokédex
Old Rod Old Rod III Allows the player to fish in bodies of water
Old Sea Map Old Sea Map III Allows players to access Faraway Island
Pokéblock Case Pokéblock Case III Holds 40 Pokéblocks
Allows admission to the Safari Zone
Allows players to participate in Pokémon ContestsE
Poké Flute Poké Flute III Awakens the player's and the opponent's sleeping Pokémon
Awakens the sleeping Snorlax on Routes 12 and 16
Powder Jar Powder Jar III Holds Berry Powder from Berry Crush
Rainbow Pass Rainbow Pass III Allows players access to all of the Sevii Islands
Red Orb III Red Orb III Use to calm Groudon
Rm Rm. 1 Key III Opens a room on the Abandoned Ship
Rm Rm. 2 Key III Opens a room on the Abandoned Ship
Rm Rm. 4 Key III Opens a room on the Abandoned Ship
Rm Rm. 6 Key III Opens a room on the Abandoned Ship
Ruby Ruby III Give to Celio along with Sapphire to set up the Network Machine of the Pokémon Network Center on One Island
In exchange for the Ruby, Celio gives the player a Rainbow Pass
Sapphire Sapphire III Give to Celio along with Ruby to set up the Network Machine of the Pokémon Network Center on One Island
Scanner Scanner III Give to Captain Stern to exchange it for a DeepSeaScale or DeepSeaTooth
Secret Key III Secret Key III Unlocks the door of Cinnabar Gym
Silph Scope III Silph Scope III Allows the Pokémon of Pokémon Tower to be seen
Soot Sack Soot Sack III Allows volcanic ash to be collected on Route 113
S.S S.S. Ticket III Allows admission to the S.S. TidalRSE or S.S. AnneFRLG
Storage Key III Storage Key III Allows a door to be opened on the Abandoned Ship
Super Rod Super Rod III Allows the player to fish in bodies of water. The best Rod of all
Tea Tea III Give to the Saffron City guards to be granted access to the city
Teachy TV Teachy TV III Teaches players basics about Pokémon battles
TM Case TM Case III Holds TMs and HMs
Town Map III Town Map III Displays a map of Kanto and the Sevii Islands
Tri-Pass Tri-Pass III Allows players to access the three northernmost Sevii Islands
Vs Vs. Seeker III Allows Trainers to be re-challenged
Wailmer Pail Wailmer Pail III Allows Berries to be watered. If watering is done correctly, the resulting Berry trees will have more Berries to pick
Allows the player to pass Sudowoodo in the Battle FrontierE
 
Key items
Generation IGeneration IIGeneration III (Orre) • Generation IVGeneration VGeneration VIGeneration VIIGeneration VIIIGeneration IX
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